Being able to run two reactions concurrently enables synthetic methods to be streamlined, but simultaneously controlling the selectivity of both reactions is an enormous challenge. Now, a directing group is used to reinvent a classic tandem reaction, activating specific sp3 C–H bonds with pinpoint accuracy.
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Jenny, S.E., Dobereiner, G.E. Tungsten’s tandem transformation. Nat. Chem. 14, 594–595 (2022). https://doi.org/10.1038/s41557-022-00953-w
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DOI: https://doi.org/10.1038/s41557-022-00953-w
