Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.


A ravel alliance

A new class of interwoven metal–organic containers, including one with a cubic architecture, twelve crossing points and a large internal volume, has now been reported. Interconversion between different self-assembled structures can be triggered by simply exchanging the associated anions.

Your institute does not have access to this article

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Fig. 1: Molecular knots and ravels.


  1. Wikoff, W. R. et al. Science 289, 2129–2133 (2000).

    CAS  Article  Google Scholar 

  2. Marenduzzo, D., Micheletti, C., Orlandini, E. & Sumners, D. W. Proc. Natl Acad. Sci. USA 110, 20081–20086 (2013).

    CAS  Article  Google Scholar 

  3. Dabrowski-Tumanski, P., Stasiak, A. & Sulkowska, J. I. PLOS One 11, e0165986 (2016).

    Article  Google Scholar 

  4. Soler, M. A. & Faísca, P. F. N. PLOS One 8, e74755 (2013).

    CAS  Article  Google Scholar 

  5. August, D. P. et al. J. Am. Chem. Soc. 142, 18859–18865 (2020).

    CAS  Article  Google Scholar 

  6. Wasserman, E. J. Am. Chem. Soc. 82, 4433–4434 (1960).

    CAS  Article  Google Scholar 

  7. Dietrich-Buchecker, C. O. & Sauvage, J.-P. Angew. Chem. Int. Ed. 28, 189–192 (1989).

    Article  Google Scholar 

  8. Fielden, S. D. P., Leigh, D. A. & Woltering, S. L. Angew. Chem. Int. Ed. 56, 11166–11194 (2017).

    CAS  Article  Google Scholar 

  9. Castle, T., Evans, M. E. & Hyde, S. T. New J. Chem. 32, 1484–1492 (2008).

    CAS  Article  Google Scholar 

  10. Li, F., Clegg, J. K., Lindoy, L. F., Macquart, R. B. & Meehan, G. V. Nat. Commun. 2, 205 (2011).

    Article  Google Scholar 

  11. Domoto, Y., Abe, M., Yamamoto, K., Kikuchi, T. & Fujita, M. Chem. Sci. 11, 10457–10460 (2020).

    CAS  Article  Google Scholar 

  12. Domoto, Y., Abe, M., Kikuchi, T. & Fujita, M. Angew. Chem. Int. Ed. 59, 3450–3454 (2020).

    CAS  Article  Google Scholar 

  13. Domoto, Y., Abe, M. & Fujita, M. J. Am. Chem. Soc. 143, 8578–8582 (2021).

    CAS  Article  Google Scholar 

  14. Inomata, Y., Sawada, T. & Fujita, M. Chem 6, 294–303 (2020).

    CAS  Article  Google Scholar 

  15. Leigh, D. A. et al. Nat. Chem. 13, 117–122 (2021).

    CAS  Article  Google Scholar 

  16. Danon, J. J. et al. Science 335, 159–162 (2017).

    Article  Google Scholar 

  17. Nierengarten, J. F., Dietrich-Buchecker, C. O. & Sauvage, J.-P. J. Am. Chem. Soc. 116, 375–376 (1994).

    CAS  Article  Google Scholar 

  18. Leigh, D. A., Pritchard, R. G. & Stephens, A. J. Nat. Chem. 6, 978–982 (2014).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Jonathan R. Nitschke.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Heard, A.W., Speakman, N.M.A. & Nitschke, J.R. A ravel alliance. Nat. Chem. 13, 824–826 (2021).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing