Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

SOLVATION

Sticky when dry

Is a nanoscale hydrophobic bowl wet or dry when dissolved in water? It turns out that the answer depends on the architecture of its rim. A molecular host decorated with four methyl groups around its rim pointing inward, rather than up, has now been shown to expel water from the bowl, making it dry and sticky.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Context-dependent hydration of a molecular host.

References

  1. Cheng, Y. K. & Rossky, P. J. Nature 392, 696–699 (1998).

    Article  CAS  Google Scholar 

  2. Hummer, G. Nat. Chem. 2, 906–907 (2010).

    Article  CAS  Google Scholar 

  3. Giovambattista, N. et al. Proc. Natl Acad. Sci. USA 105, 2274–2279 (2008).

    Article  CAS  Google Scholar 

  4. Barnett, J. W. et al. Nat. Chem. https://doi.org/10.1038/s41557-020-0458-8 (2020).

    Article  PubMed  Google Scholar 

  5. Patel, A. J. et al. J. Phys. Chem. B 116, 2498–2503 (2012).

    Article  CAS  Google Scholar 

  6. Gibb, C. L. D. & Gibb, B. C. J. Am. Chem. Soc. 126, 11408–11409 (2004).

    Article  CAS  Google Scholar 

  7. Patel, A. J., Varilly, P. & Chandler, D. J. Phys. Chem. B 114, 1632–1637 (2010).

    Article  CAS  Google Scholar 

  8. Chandler, D. Nature 437, 640–647 (2005).

    Article  CAS  Google Scholar 

  9. Anishkin, A. & Sukharev, S. Biophys. J. 86, 2883–2895 (2004).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shekhar Garde.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Garde, S. Sticky when dry. Nat. Chem. 12, 587–588 (2020). https://doi.org/10.1038/s41557-020-0498-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41557-020-0498-0

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing