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NUCLEIC ACID NANOTECHNOLOGY

RNA returns to the fold

RNA has multiple roles in biology, enabled by its structural diversity. Now, artificially grafted RNA motifs have been encoded in a single RNA strand to form self-assembling nanostructures with controlled geometry and function.

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Fig. 1: RNA nanostructures based on branched kissing-loop motifs.

References

  1. Zhang, F. & Yan, H. Nature 552, 34–35 (2017).

    Article  CAS  Google Scholar 

  2. Liu, D. et al. Nat. Chem. https://doi.org/10.1038/s41557-019-0406-7 (2020).

  3. Seeman, N. J. Theor. Biol. 99, 237–247 (1982).

    Article  CAS  Google Scholar 

  4. Delebecque, C., Lindner, A., Silver, P. & Aldaye, F. Science 333, 470–474 (2011).

    Article  CAS  Google Scholar 

  5. Krissanaprasit, A. et al. Adv. Mater. 31, 1808262 (2019).

    Article  Google Scholar 

  6. Cui, D. et al. Sci. Rep. 5, 10726 (2015).

    Article  Google Scholar 

  7. Grabow, W. & Jaeger, L. Acc. Chem. Res. 47, 1871–1880 (2014).

    Article  CAS  Google Scholar 

  8. Geary, C., Rothemund, P. & Andersen, E. Science 345, 799–804 (2014).

    Article  CAS  Google Scholar 

  9. Li, M. et al. Nat. Commun. 9, 2196 (2018).

    Article  Google Scholar 

  10. Ong, L. L. et al. Nature 552, 72–77 (2017).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Chenxiang Lin.

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Shen, Q., Lin, C. RNA returns to the fold. Nat. Chem. 12, 221–222 (2020). https://doi.org/10.1038/s41557-020-0432-5

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