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Untangling knotty problems

The synthesis of molecular knots has been a major achievement in the field of chemical topology, but only a few relatively simple ones have been made so far. A route based on a weaving approach has now been used to make a seven-crossing knot and could offer a route to more complicated structures.

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Fig. 1: Strategies to make molecular knots.


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Correspondence to Paul E. Kruger.

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Preston, D., Kruger, P.E. Untangling knotty problems. Nat. Chem. 13, 114–116 (2021).

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