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On the origin of the blind chicken molecule

A curious chemical structure from the imagination of a child will forever be connected with a cancer diagnosis for one particular family. And now the challenge is on to make this molecule a reality.

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Fig. 1: Filucca and her ‘blind chicken’ molecule.
Fig. 2: Translating the blind chicken molecule into a plausible synthetic target.


The authors and their closest family are grateful to Majbrith Hørsted Toustrup for her decision to speak her mind on a September day in 2018 and for unconditional help and support from family and friends through a difficult period. Finally, we thank the exceptionally skilled surgical teams and the paediatric oncology unit at Aarhus University Hospital, Denmark.

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F.S.B. conceived of and built the blind chicken molecule without having detailed knowledge of chemistry, T.B.P. — unwittingly — caused the situation that resulted in the construction of the blind chicken molecule, analysed the structure, and wrote the article with consent and input from F.S.B.

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Correspondence to Thomas Bjørnskov Poulsen.

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Bjørnskov, F.S., Poulsen, T.B. On the origin of the blind chicken molecule. Nat. Chem. 12, 2–3 (2020).

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