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AMINATION

Nitrogen gets radical

Nature Chemistry volume 11, pages 396–398 (2019)Cite this article

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The direct formation of C–N bonds onto arenes provides a simple route to synthesize a variety of important products. Now, formation of a highly polarized, aminium radical cation enables direct C–H amination, allowing the coupling of an exceptionally broad range of alkyl amines and arenes.

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Fig. 1: The development of a broadly applicable, photocatalytic method for intermolecular C–H amination of a wide range of arenes with alkyl amines.

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  1. Department of Chemistry and Biochemistry at The Ohio State University, Columbus, OH, USA

    David Nagib

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  1. David Nagib
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Correspondence to David Nagib.

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Twitter: @nagiblab

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Nagib, D. Nitrogen gets radical. Nat. Chem. 11, 396–398 (2019). https://doi.org/10.1038/s41557-019-0259-0

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