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SUPEROXIDE DISMUTASE MIMICS

Redox activity goes organic

Superoxide dismutase mimics can help regulate the levels of O2•− in the body, but typically rely on redox-active metals that are toxic in their free form. Now, a complex featuring a redox-active quinol moiety complexed to a redox-inactive zinc centre has been shown to catalyse O2•− dismutation.

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Fig. 1: Spontaneous and enzymatic removal of O2•− in aqueous solution.

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Correspondence to Diane E. Cabelli.

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Cabelli, D.E. Redox activity goes organic. Nature Chem 10, 1173–1175 (2018). https://doi.org/10.1038/s41557-018-0180-y

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