Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

Reconstituting the dynamic steady states of actin networks in vitro

Nature Cell Biology volume 26, pages 494–497 (2024)Cite this article

Subjects

Despite the constant renewal of their components, cellular actin networks maintain their overall appearance, through a subtle balance of filament assembly and disassembly. This balance is key to the remodelling of cellular architecture. We discuss the significance of in vitro reconstitutions in deciphering the complexity of actin regulation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Dynamic steady states of actin networks.

References

  1. Goode, B. L., Eskin, J. & Shekhar, S. J. Cell Biol. 222, 1–20 (2023).

    Article  Google Scholar 

  2. Mohapatra, L., Goode, B. L., Jelenkovic, P., Phillips, R. & Kondev, J. Annu. Rev. Biophys. 45, 85–116 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Landino, J. et al. Curr. Biol. 31, 5613–5621.e5 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Malik-Garbi, M. et al. Nat. Phys. 15, 509–516 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Tan, T. H. et al. Sci. Adv. 4, eaar2847 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Sakamoto, R., Miyazaki, M. & Maeda, Y. T. Phys. Rev. Res. 5, 013208 (2023).

    Article  CAS  Google Scholar 

  7. Akin, O. & Mullins, R. D. Cell 133, 841–851 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Manhart, A. et al. Elife 8, 1–37 (2019).

    Article  Google Scholar 

  9. Colin, A. et al. EMBO J. 42, e112717 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Sonal et al. J. Cell Sci. 132, jcs219899 (2019).

    Article  CAS  Google Scholar 

  11. Watanabe, N., Tohyama, K. & Yamashiro, S. Biochem. Biophys. Res. Commun. 506, 323–329 (2018).

    Article  CAS  PubMed  Google Scholar 

  12. Bieling, P. et al. Cell 164, 115–127 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Cao, L. et al. Elife 7, 1–24 (2018).

    Google Scholar 

  14. Boujemaa-Paterski, R. et al. Nat. Commun. 8, 655 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  15. Raz-Ben Aroush, D. et al. Curr. Biol. 27, 2963–2973.e14 (2017).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

M.T. and L.B. thank the CytoMorpho Lab for critical reading and providing constructive comments. This work was supported by a European Research Council consolidator grant (771599) and proof-of-concept grant (780458) (to M.T.) and by an advanced grant (741773) (AAA) (to L.B.).

Author information

Authors and Affiliations

  1. Université Paris Sciences et Lettres, CEA, ESPCI, Institut Pierre-Gilles de Gennes, CytoMorpho Lab, Paris, France

    Manuel Théry & Laurent Blanchoin

  2. Université Grenoble-Alpes, CEA, CNRS, INRA, Interdisciplinary Research Institute of Grenoble, CytoMorpho Lab, Grenoble, France

    Manuel Théry & Laurent Blanchoin

Authors
  1. Manuel Théry
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Laurent Blanchoin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Manuel Théry or Laurent Blanchoin.

Ethics declarations

Competing interests

The authors declare no competing interests.

Peer review

Peer review information

Nature Cell Biology thanks Thomas Pollard and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Théry, M., Blanchoin, L. Reconstituting the dynamic steady states of actin networks in vitro. Nat Cell Biol 26, 494–497 (2024). https://doi.org/10.1038/s41556-024-01379-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41556-024-01379-x

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing