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Organelles

Endoplasmic reticulum tethering by desmosomes

Nature Cell Biology volume 25, pages 796–797 (2023)Cite this article

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Desmosomes and keratin are now found to regulate the distribution and dynamics of the endoplasmic reticulum (ER). This suggests that a range of ER functions may be coordinated by this intercellular adhesive and cytoskeletal network.

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Fig. 1: Possible consequences of ER-desmosome tethering.

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Author information

Authors and Affiliations

  1. Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA

    Robert M. Harmon

  2. Pulmonary Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA

    Cara J. Gottardi

  3. Cell & Developmental Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA

    Cara J. Gottardi

Authors
  1. Robert M. Harmon
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  2. Cara J. Gottardi
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Correspondence to Robert M. Harmon or Cara J. Gottardi.

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The authors declare no competing interests.

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Harmon, R.M., Gottardi, C.J. Endoplasmic reticulum tethering by desmosomes. Nat Cell Biol 25, 796–797 (2023). https://doi.org/10.1038/s41556-023-01144-6

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