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Mediterranean mechanisms of longevity

The Mediterranean diet correlates with increased human lifespan; it is rich in foods with high levels of cis-monounsaturated fatty acids (MUFAs), such as olive oil. A study now shows that MUFAs stimulate a lipid droplet–peroxisome organelle network to decrease lipid oxidation and protect cell membranes during ageing.

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Fig. 1: Overview of how MUFAs act to decrease age-related membraned damage.


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Correspondence to Alexander Richard Mendenhall.

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Mendenhall, A.R. Mediterranean mechanisms of longevity. Nat Cell Biol 25, 627–628 (2023).

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