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PROTEIN AGGREGATION

Membranes regulate biomolecular condensates

Biomolecular condensation has emerged as a fundamental mechanism for cellular organization, but less is known about the regulation of condensate subcellular location and size. A new study reports that membrane tethering of protein and RNA directly influences the assembly, size and material properties of ribonucleic condensates.

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Fig. 1: Membrane localization controls the nucleation and size of condensates.

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Correspondence to Lindsay B. Case.

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Case, L.B. Membranes regulate biomolecular condensates. Nat Cell Biol 24, 404–405 (2022). https://doi.org/10.1038/s41556-022-00892-1

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