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Surveying the mitochondrial proteome

Mitochondrial-derived vesicles (MDVs) transfer mitochondrial content to lysosomes and peroxisomes. A study now reveals that MDVs deliver β-barrel proteins and fully assembled mitochondrial complexes for lysosomal degradation, establishing an important role for MDVs in mitochondrial protein quality control.

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Fig. 1: Function and formation of MDVs.


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Correspondence to Thomas Becker.

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Winter, D., Becker, T. Surveying the mitochondrial proteome. Nat Cell Biol 23, 1216–1217 (2021).

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