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REGENERATION

Stem cell progeny liaisons in regeneration

Stem cells are the functional units of tissue repair but do not act alone. Studies on flatworms now reveal specialized populations of differentiated cells that transiently emerge to coordinate whole-body regeneration. The stem-cell-centric view of repair processes must be revised to account for the importance of cell fate dynamics beyond the niche.

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Fig. 1: Identifying TRACS in planaria.

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Correspondence to Elaine Fuchs.

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Ellis, S.J., Fuchs, E. Stem cell progeny liaisons in regeneration. Nat Cell Biol 23, 932–933 (2021). https://doi.org/10.1038/s41556-021-00751-5

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