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Nutrient-sensitive heterochromatization by TOR

Facultative heterochromatin occurs at regions that contain developmentally regulated genes. A study now reveals that the nutrient-sensitive TORC1 signalling pathway affects the RNA elimination machinery, thereby regulating the timely expression of meiotic genes embedded in facultative heterochromatic loci.

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Fig. 1: Formation of facultative heterochromatin at meiotic genes.


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Correspondence to Ronit Weisman.

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Weisman, R. Nutrient-sensitive heterochromatization by TOR. Nat Cell Biol 23, 214–216 (2021).

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