Anorexia commonly develops in patients with advanced cancer and is closely associated with cachexia. A new study shows that anorexia emerges earlier than cachexia in both Drosophila and mouse tumour models and that tumour-derived humoral factors induce anorexia by systemically dysregulating neuropeptides in the brain.
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Wang, G., Zhang, H. & Lyden, D. Tumour-regulated anorexia preceding cachexia. Nat Cell Biol 23, 111–113 (2021). https://doi.org/10.1038/s41556-021-00635-8
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DOI: https://doi.org/10.1038/s41556-021-00635-8
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