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Prostate cancer hijacks the microenvironment

Prostate cancer is difficult to treat because of molecular, cellular and clinical heterogeneity. Using single-cell RNA sequencing, a recent study reveals unexpected transcriptomic reprograming in immune cells and non-immune components of the tumour microenvironment, which may lead to viable therapeutic approaches against prostate cancer.

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Fig. 1: Prostate cancer enables the establishment of a metastatic TME niche.

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Correspondence to Mark A. Rubin.

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Thienger, P., Rubin, M.A. Prostate cancer hijacks the microenvironment. Nat Cell Biol 23, 3–5 (2021). https://doi.org/10.1038/s41556-020-00616-3

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