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CELL MIGRATION

Migrasomes take center stage

Nature Cell Biology volume 21, pages 918–920 (2019)Cite this article

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Migrasomes are a recently discovered type of extracellular vesicles that are characteristically generated along retraction fibers in migrating cells. Two studies now show how migrasomes are formed and how they function in the physiologically relevant context of the developing zebrafish embryo.

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Fig. 1: Migration-depended mechanical force triggers migrasome formation.
Fig. 2: Mesendoderm-derived migrasomes regulate clustering of DFCs.

References

  1. Perrimon, N., Pitsouli, C. & Shilo, B. Z. Cold Spring Harb. Perspect. Biol. 4, a005975 (2012).

    Article  Google Scholar 

  2. Sever, R. & Brugge, J.S. Cold Spring Harb. Perspect. Med. 5, a006098 (2015).

    Article  Google Scholar 

  3. Maas, S. L. N., Breakefield, X. O. & Weaver, A. M. Trends Cell Biol. 27, 172–188 (2017).

    Article  CAS  Google Scholar 

  4. Meldolesi, J. Curr. Biol. 28, R435–R444 (2018).

    Article  CAS  Google Scholar 

  5. Cruz, L., Romero, J. A. A., Iglesia, R. P. & Lopes, M. H. Front. Cell Dev. Biol. 6, 94 (2018).

    Article  Google Scholar 

  6. Tanaka, Y., Okada, Y. & Hirokawa, N. Nature 435, 172–177 (2005).

    Article  CAS  Google Scholar 

  7. Ma, L. et al. Cell Res. 25, 24–38 (2015).

    Article  CAS  Google Scholar 

  8. Huang, Y. et al. Nat. Cell Biol. https://doi.org/10.1038/s41556-019-0367-5 (2019).

  9. Jiang, D. et al. Nat. Cell Biol. https://doi.org/10.1038/s41556-019-0358-6 (2019).

  10. Rohde, L. A. & Heisenberg, C. P. Int. Rev. Cytol. 261, 159–192 (2007).

    Article  CAS  Google Scholar 

  11. Solnica-Krezel, L. & Sepich, D. S. Annu. Rev. Cell Dev. Biol. 28, 687–717 (2012).

    Article  CAS  Google Scholar 

  12. Matsui, T., Ishikawa, H. & Bessho, Y. Front. Cell Dev. Biol. 3, 27 (2015).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Institute of Science and Technology Austria, Klosterneuburg, Austria

    Stefania Tavano & Carl-Philipp Heisenberg

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  1. Stefania Tavano
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  2. Carl-Philipp Heisenberg
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Correspondence to Carl-Philipp Heisenberg.

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The authors declare no competing interests.

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Tavano, S., Heisenberg, CP. Migrasomes take center stage. Nat Cell Biol 21, 918–920 (2019). https://doi.org/10.1038/s41556-019-0369-3

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