Supplementary Figure 3: Differential m6As among human tissues. | Nature Cell Biology

Supplementary Figure 3: Differential m6As among human tissues.

From: The RNA N6-methyladenosine modification landscape of human fetal tissues

Supplementary Figure 3

a. Circos plot of tissue-differential m(6)As across the genome in brain (orange), heart (blue), kidney (green), liver (gray), lung (acen), muscle (purple), placenta (red), and stomach (yellow), respectively.b. MeRIP enrichment (upper) and expression level (lower) of two lung-differential m(6)A peaks on ECT2L and WNT4, and one stomach-differential peak on TMEM184A. Enrichment of IPed versus input RNA and the expression level is normalize against ZNF384, which is a conserved m(6)A peak across all tissues. MeRIP-qPCR and qPCR were performed once with two technical replicates obtained and shown.NA means the RNA level is too low to be detected by qPCR (see source data in Supplementary Table 5).

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