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STEM CELLS

Long noncoding RNAs in gut stem cells

The intestinal crypt has become the prototype compartment to investigate adult stem cell biology, and the list of identified intestinal stem cell (ISC) markers is already extensive. A comprehensive study now uncovers an additional layer in ISC regulation by introducing long noncoding RNA lncGata6 to the stem cell repertoire.

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Fig. 1: Function of intestinal stem cell specific lncGata6.

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Correspondence to Pantelis Hatzis or Hugo J. G. Snippert.

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Hatzis, P., Snippert, H.J.G. Long noncoding RNAs in gut stem cells. Nat Cell Biol 20, 1106–1107 (2018). https://doi.org/10.1038/s41556-018-0208-y

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