Supplementary Figure 4: Characterization of kinetochore expansion. Related to Figure 3. | Nature Cell Biology

Supplementary Figure 4: Characterization of kinetochore expansion. Related to Figure 3.

From: Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis

Supplementary Figure 4

(a) Cartoon depicting the effect of ZW10 or Spindly depletion on the expandable module of the kinetochore (green), KMN network (blue) and CCAN (red). (b-c) Immunostaining with the indicated antibodies (b) and quantification (c) of kinetochore levels in cells from one of the experiments shown in Figure 3e,f. The graph in (c) shows the mean kinetochore intensity normalized to the values of the control. Control is siGAPDH. See Supplementary Table 3 for source data.

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