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NON-CODING RNA

A lncRNA GUARDINg genome integrity

A coordinated DNA damage response mediated by p53 to repair DNA lesions or to promote apoptosis is essential for maintenance of genome stability. A study now unveils the long non-coding RNA GUARDIN as a component of this pathway, which protects genome integrity in a pleiotropic fashion.

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Author information

Affiliations

  1. Department of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research, University of Navarra, Pamplona, Spain

    • Elena Grossi
    •  & Maite Huarte
  2. Health Research Institute of Navarra (IdiSNA), Pamplona, Spain

    • Elena Grossi
    •  & Maite Huarte

Authors

  1. Search for Elena Grossi in:

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Competing interests

The authors declare no competing interests.

Corresponding author

Correspondence to Maite Huarte.