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Exosomes deliver ROS for regeneration

Inflammation and reactive oxygen species (ROS) production after central nervous system injury are thought to enhance tissue damage and hamper neuronal regeneration. Evidence now suggests that NADPH2 oxidase delivery from macrophages to injured neurons through extracellular vesicles, promotes ROS signalling and axon recovery.

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Correspondence to Eva-Maria Krämer-Albers.

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Further reading

Fig. 1: ROS signalling in sensory nerve regeneration.