To overcome the finite supply of muscle stem cells available for cell therapy, a study now describes a strategy for obtaining an unlimited source of myogenic progenitors derived from human pluripotent cells. Two neuronal cell surface receptors facilitate the selection of a population with enhanced regenerative potential.
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Ho, A.T.V., Blau, H.M. Muscling toward therapy with ERBB3 and NGFR. Nat Cell Biol 20, 6–7 (2018). https://doi.org/10.1038/s41556-017-0015-x
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DOI: https://doi.org/10.1038/s41556-017-0015-x