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Learning spatial cellular motifs predictive of the responses of patients to cancer treatments

Graph deep learning applied to multiplexed immunofluorescence data from tumour microenvironments reveals spatial cellular structures that are indicative of cancer prognosis.

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Fig. 1: SPACE-GM identifies key spatial structures from graphs.

References

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This is a summary of: Wu, Z. et al. Graph deep learning for the characterization of tumour microenvironments from spatial protein profiles in tissue specimens. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-022-00951-w (2022).

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Learning spatial cellular motifs predictive of the responses of patients to cancer treatments. Nat. Biomed. Eng 6, 1328–1329 (2022). https://doi.org/10.1038/s41551-022-00958-3

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