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Sutureless gastrointestinal anastomoses

An adhesive hydrogel patch made from off-the-shelf materials seals and aids the healing of gastrointestinal-tissue defects without the need for sutures, as shown with the repair of gastrointestinal leaks in live rats and pigs.

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Fig. 1: An adhesive patch for the sutureless sealing of anastomotic gastrointestinal leaks.
Fig. 2: Mechanisms of adhesion, and conditions for the testing of adhesives for the repair of gastrointestinal leaks.


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Correspondence to Inge K. Herrmann.

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Competing interests

A.H.C.A. and I.K.H. are inventors on the patent application ‘Kit comprising adhesive hydrogel and impregnating fluid’ (PCT/EP2022/051137). The other authors declare no competing interests.

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Anthis, A.H.C., Schlegel, A.A., Hartel, M. et al. Sutureless gastrointestinal anastomoses. Nat. Biomed. Eng 6, 1089–1091 (2022).

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