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Enhanced DNA libraries for methylation analysis

Nature Biomedical Engineering volume 5, pages 490–492 (2021)Cite this article

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An efficient protocol for the preparation of DNA libraries for the analysis of methylation patterns in cell-free DNA in plasma enhances the sensitivity of bisulfite sequencing for the early detection of lung cancer.

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Fig. 1: Three library-preparation workflows for bisulfite sequencing.

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  1. Department of Data Science, Recursion Pharmaceuticals, Salt Lake City, UT, USA

    Imran S. Haque

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  1. Imran S. Haque
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Correspondence to Imran S. Haque.

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Competing interests

I.S.H. is a former employee of Freenome and a shareholder in the company.

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Haque, I.S. Enhanced DNA libraries for methylation analysis. Nat Biomed Eng 5, 490–492 (2021). https://doi.org/10.1038/s41551-021-00750-9

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