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DRUG DESIGN

Supramolecularly stabilized diabetes drugs

Nature Biomedical Engineering volume 4, pages 481–482 (2020)Cite this article

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The stabilization of co-administered insulin and pramlintide with cucurbit[7]uril-conjugated poly(ethylene glycol) in diabetic pigs enhances the overlap of their therapeutic windows.

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Fig. 1: The overlap of the functional windows of co-administered insulin and pramlintide is enhanced when the drugs are modified with CB[7]–PEG.

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Authors and Affiliations

  1. Nordic Bioscience Biomarkers and Research, Herlev, Denmark

    Kim Henriksen & Morten A. Karsdal

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  1. Kim Henriksen
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  2. Morten A. Karsdal
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Correspondence to Kim Henriksen.

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K.H. and M.A.K. are employees and stockholders of Nordic Bioscience A/S.

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Henriksen, K., Karsdal, M.A. Supramolecularly stabilized diabetes drugs. Nat Biomed Eng 4, 481–482 (2020). https://doi.org/10.1038/s41551-020-0558-1

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