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A new opening for orally taken peptide drugs

Negatively charged nanoparticles of about 50 nm in size permit the oral delivery of insulin and other peptide drugs by temporally enhancing the permeability of the intestinal wall.

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Fig. 1: Mechanisms of tight junction opening for enhancing the permeability of the intestinal wall.


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Correspondence to Per Artursson.

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Artursson, P., Lundquist, P. A new opening for orally taken peptide drugs. Nat Biomed Eng 4, 12–13 (2020).

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