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OPTOACOUSTIC IMAGING

Maps of neuronal activity across the mouse brain

Nature Biomedical Engineering volume 3, pages 335–336 (2019)Cite this article

High-speed optoacoustic tomography can monitor the neural activity of a whole mouse brain, by using a genetically encoded calcium sensor originally developed for fluorescence microscopy.

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Fig. 1: Functional optoacoustic imaging of a whole mouse brain.

References

  1. Vincent, P. et al. EMBO Rep. 11, 1154–1161 (2006).

    Article  Google Scholar 

  2. Yao, J. & Wang, L. V. Curr. Opin. Chem. Biol. 45, 104–112

  3. Gottschalk, S. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-019-0372-9 (2019).

    Article  PubMed  Google Scholar 

  4. Wang, L. V. & Yao, J. Nat. Methods 13, 627–638 (2016).

    Article  CAS  Google Scholar 

  5. Deán-Ben, X. L. et al. Light Sci. Appl. 5, e16201 (2016).

    Article  Google Scholar 

  6. Marvin, J. S. et al. Nat. Methods 10, 162–170 (2013).

    Article  CAS  Google Scholar 

  7. Patriarchi, T. et al. Science 360, eaat4422 (2018).

    Article  Google Scholar 

  8. Miao, Q. & Pu, K. Bioconjug. Chem. 27, 2808–2823 (2016).

    Article  CAS  Google Scholar 

  9. Knox, H. J. & Chan, J. Acc. Chem. Res. 51, 2897–2905 (2018).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, CA, USA

    Alessio Andreoni & Lin Tian

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  1. Alessio Andreoni
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  2. Lin Tian
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Correspondence to Lin Tian.

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Andreoni, A., Tian, L. Maps of neuronal activity across the mouse brain. Nat Biomed Eng 3, 335–336 (2019). https://doi.org/10.1038/s41551-019-0403-6

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