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NANOMEDICINE

A potent targeted cancer nanotherapeutic

Nature Biomedical Engineeringvolume 3pages248250 (2019) | Download Citation

An antibody-modified nanoparticle encapsulating a pH-sensitive taxane prodrug, and targeting an overexpressed receptor in tumours, improves the tolerability and anticancer efficacy of the active drug in multiple animal models.

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Affiliations

  1. Children’s Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, New South Wales, Australia

    • Ernesto Moles
    •  & Maria Kavallaris
  2. ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and Australian Centre for Nanomedicine, University of New South Wales, Sydney, New South Wales, Australia

    • Ernesto Moles
    •  & Maria Kavallaris
  3. School of Women’s and Children’s Health, University of New South Wales, Sydney, New South Wales, Australia

    • Ernesto Moles
    •  & Maria Kavallaris

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Correspondence to Maria Kavallaris.

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https://doi.org/10.1038/s41551-019-0390-7

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