Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:


Coated glucose sensors dodge recalibration

Coating continuous glucose-monitoring sensors with zwitterionic polymer reduces early inflammatory responses and signal noise after sensor implantation in live animals, and improves the performance of the sensors without the need for additional recalibration.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: A zwitterionic-polymer coating improves the accuracy of glucose sensors.


  1. Dondossola, E. et al. Nat. Biomed. Eng. 1, 0007 (2017).

    Article  Google Scholar 

  2. Zhang, L. et al. Nat. Biotechnol. 31, 553–556 (2013).

    Article  CAS  Google Scholar 

  3. Doloff, J. C. et al. Nat. Mater. 16, 671–680 (2017).

    Article  CAS  Google Scholar 

  4. Ward, W. K. J. Diabetes Sci. Technol. 2, 768–777 (2008).

    Article  Google Scholar 

  5. Gifford, R. ChemPhysChem 14, 2032–2044 (2013).

    Article  CAS  Google Scholar 

  6. Rodbard, D. Diabetes Technol. Ther. 18 (Suppl. 2), S3–S13 (2016).

    PubMed  Google Scholar 

  7. Novak, M. T., Yuan, F. & Reichert, W. M. Diabetes Sci. Technol. 7, 1547–1560 (2013).

    Article  Google Scholar 

  8. Nichols, S. P. et al. Chem. Rev. 113, 2528–2549 (2013).

    Article  CAS  Google Scholar 

  9. Xie, X. et al. Nat. Biomed. Eng. (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  10. Abbott Diabetes Care Inc. Freestyle Libre 14 Day Flash Glucose Monitoring System - P160030/S017 (FDA, 2018);

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Zhiqiang Cao.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhang, E., Cao, Z. Coated glucose sensors dodge recalibration. Nat Biomed Eng 2, 881–882 (2018).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing