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Hyperthermia-induced drug delivery in humans

Nature Biomedical Engineeringvolume 2pages637639 (2018) | Download Citation

A clinical study shows the feasibility and safety of the intratumoral release of an anticancer drug encapsulated in thermosensitive liposomes by heating the patient’s tumour via focused ultrasound.

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Author information

Affiliations

  1. Physical Sciences Platform, Sunnybrook Research Institute and Department of Medical Biophysics, and Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

    • Kullervo Hynynen

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Competing interests

K.H. owns stocks in, is a board member of and receives research funding from FUS Instruments Inc. (a manufacturer of pre-clinical ultrasound research devices) and Harmonic Inc. (which is developing thermal ablation devices for clinical use).

Corresponding author

Correspondence to Kullervo Hynynen.

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DOI

https://doi.org/10.1038/s41551-018-0297-8

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