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Holographic diagnosis of lymphoma

A holographic approach relying on small-molecule chromogens enables a rapid and inexpensive test for the accurate classification of aggressive lymphoma at the point of care.

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Fig. 1: Standalone device, based on contrast-enhanced microholography, for the diagnosis of lymphoma.


  1. 1.

    Cancer factsheet (World Health Organization, 2018).

  2. 2.

    Yager, P., Domingo, G. J. & Gerdes, J. Annu. Rev. Biomed. Eng. 10, 107–144 (2008).

    Article  PubMed  CAS  Google Scholar 

  3. 3.

    Im, H. et al. Nat. Biomed. Eng. (2018).

    Article  Google Scholar 

  4. 4.

    Im, H. et al. Proc. Natl Acad. Sci. USA 112, 5613–5618 (2015).

    Article  PubMed  CAS  Google Scholar 

  5. 5.

    Pathania, D. et al. Theranostics 6, 1603–1610 (2016).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  6. 6.

    Saliba, A.-E. et al. Proc. Natl Acad. Sci. USA 107, 14524–14529 (2010).

    Article  PubMed  Google Scholar 

  7. 7.

    Mitchell, P. S. et al. Proc. Natl Acad. Sci. USA 105, 10513–10518 (2008).

    Article  PubMed  Google Scholar 

  8. 8.

    Lawrie, C. H. et al. Br. J. Haematol. 141, 672–675 (2008).

    Article  PubMed  Google Scholar 

  9. 9.

    Hsieh, C.-H. et al. Sci. Rep. 8, 10684 (2018).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

Download references

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Correspondence to David Erickson.

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Kopparthy, V.L., Snodgrass, R. & Erickson, D. Holographic diagnosis of lymphoma. Nat Biomed Eng 2, 631–632 (2018).

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