Polymer-coated gold nanoparticles carrying the CRISPR components for knocking out, in the striatum of adult mice with fragile X syndrome, a gene implied in the syndrome’s pathophysiology rescue the mice from the exaggerated repetitive behaviours characteristic of the syndrome’s phenotype.
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Li, Y., Glass, Z. & Xu, Q. Rescued from the fate of neurological disorder. Nat Biomed Eng 2, 469–470 (2018). https://doi.org/10.1038/s41551-018-0267-1
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DOI: https://doi.org/10.1038/s41551-018-0267-1
