The sustained delivery of extracellular vesicles, secreted by induced-pluripotent-stem-cell-derived cardiomyocytes, through a hydrogel patch promotes cardiac recovery after myocardial infarction in rats.
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References
Cambria, E. et al. npj Regen. Med. 2, 17 (2017).
Tzahor, E. & Poss, K. D. Science 356, 1035–1039 (2017).
Kim, S. M. & Kim, H. S. Stem Cell Invest. 4, 74 (2017).
van Niel, G., D'Angelo, G. & Raposo, G. Nat. Rev. Mol. Cell Biol. 19, 213–228 (2018).
Gallet, R. et al. Eur. Heart J. 38, 201–211 (2017).
Khan, M. et al. Circ. Res. 117, 52–64 (2015).
Bian, S. et al. J. Mol. Med. 92, 387–397 (2014).
Mackie, A. R. et al. Circ. Res. 111, 312–321 (2012).
Wallace, D. G. & Rosenblatt, J. Adv. Drug Del. Rev. 55, 1631–1649 (2003).
Taylor, D. A., Sampaio, L. C. & Gobin, A. Am. J. Transplant. 14, 2448–2459 (2014).
Liu, B. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-018-0229-7 (2018).
Wang, L. L. et al. Nat. Biomed. Eng. 1, 983–992 (2017).
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Heallen, T.R., Martin, J.F. Heart repair via cardiomyocyte-secreted vesicles. Nat Biomed Eng 2, 271–272 (2018). https://doi.org/10.1038/s41551-018-0239-5
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DOI: https://doi.org/10.1038/s41551-018-0239-5
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