News & Views | Published:

Diagnostic Nanoprobes

Optical detection of abnormal skin scarring

Nature Biomedical Engineeringvolume 2pages201202 (2018) | Download Citation

Topically applied spherical nucleic acids targeting an intracellular mRNA biomarker associated with abnormal scarring enable the fluorescent detection of abnormal scars during wound healing.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    Byron, S. A., Van Keuren-Jensen, K. R., Engelthaler, D. M., Carpten, J. D. & Craig, D. W. Nat. Rev. Genet. 17, 257–271 (2016).

  2. 2.

    Li, Y. et al. Clin. Cancer Res. 10, 8442–8450 (2004).

  3. 3.

    Kremer, L. S. et al. Nat. Commun. 8, 15824 (2017).

  4. 4.

    Cummings, B. B. et al. Sci. Transl. Med. 9, eaal5209 (2017).

  5. 5.

    Tan, S. C. & Yiap, B. C. J. Biomed. Biotechnol. 2009, 574398 (2009).

  6. 6.

    Sorg, H., Tilkorn, D. J., Hager, S., Hauser, J. & Mirastschijski, U. Eur. Surg. Res. 58, 81–94 (2017).

  7. 7.

    Yeo, D. C., Wiraja, C., Paller, A. S., Mirkin, C. A. & Xu, C. Nat. Biomed. Eng.. https://doi.org/10.1038/s41551-018-0218-x (2018).

  8. 8.

    Prigodich, A. E. et al. Anal. Chem. 84, 2062–2066 (2012).

  9. 9.

    Halo, T. L. et al. Proc. Natl Acad. Sci. USA 111, 17104–17109 (2014).

  10. 10.

    Seferos, D. S., Prigodich, A. E., Giljohann, D. A., Patel, P. C. & Mirkin, C. A. Nano Lett. 9, 308–311 (2009).

Download references

Author information

Affiliations

  1. Department of NanoEngineering and Moores Cancer Center, University of California San Diego, San Diego, CA, USA

    • Ronnie H. Fang
    •  & Liangfang Zhang

Authors

  1. Search for Ronnie H. Fang in:

  2. Search for Liangfang Zhang in:

Corresponding author

Correspondence to Liangfang Zhang.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/s41551-018-0222-1

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing