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Diagnostic Nanoprobes

Optical detection of abnormal skin scarring

Topically applied spherical nucleic acids targeting an intracellular mRNA biomarker associated with abnormal scarring enable the fluorescent detection of abnormal scars during wound healing.

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Fig. 1: Gold nanoparticles with spherical nucleic acids for the detection of intracellular mRNA (NanoFlares).

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Correspondence to Liangfang Zhang.

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Fang, R.H., Zhang, L. Optical detection of abnormal skin scarring. Nat Biomed Eng 2, 201–202 (2018). https://doi.org/10.1038/s41551-018-0222-1

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