Commensal microbes engineered to convert natural compounds found in cruciferous vegetables into molecules with anticancer properties prevent carcinogenesis and cause the regression of colorectal cancer in mice fed with a vegetable diet.
This is a preview of subscription content, access via your institution
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$99.00 per year
only $8.25 per issue
Rent or buy this article
Prices vary by article type
Prices may be subject to local taxes which are calculated during checkout
Song, M., Garrett, W. S. & Chan, A. T. Gastroenterology 148, 1244–1260 (2015).
O’Keefe, S. J. Nat. Rev. Gastroenterol. Hepatol. 13, 691–706 (2016).
Plottel, C. S. & Blaser, M. J. Cell. Host Microbe 10, 324–335 (2011).
Abreu, M. T. & Peek, R. M. Jr. Gastroenterology 146, 1534–1546 (2014).
Rook, M. G. & Garrett, W. S. Nat. Rev. Immunol. 16, 341–352 (2016).
Thomas, R. M. & Jobin, C. Trends Cancer 1, 24–35 (2015).
Sinha, R. et al. PLoS ONE 11, e0152126 (2016).
Song, M. & Chan, A. T. Curr. Colorect. Cancer Rep. https://doi.org/10.1007/s11888-017-0389-y (2017).
Ho, C. L. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-017-0181-y (2018).
Baron, J. A. et al. N. Engl. J. Med. 373, 1519–1530 (2015).
Baron, J. A. et al. N. Engl. J. Med. 340, 101–107 (1999).
Jiao, L. et al. J. Natl Cancer Inst. https://doi.org/10.1093/jnci/djx117 (2018).
Toledo, E. et al. JAMA Intern. Med. 175, 1752–1760 (2015).
About this article
Cite this article
Drew, D.A., Chan, A.T. Towards a cancer-chemopreventive diet. Nat Biomed Eng 2, 6–7 (2018). https://doi.org/10.1038/s41551-017-0186-6