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Towards safe therapy for immunodeficiency

Nature Biomedical Engineering volume 1, pages 937–938 (2017)Cite this article

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A humanized mouse model of X-linked severe combined immunodeficiency suggests that the safety of correcting the human IL2RG gene in haematopoietic stem cells depends on both gene-correction frequency and the conditioning regimen used before cell transplantation.

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Authors and Affiliations

  1. Department of Hematology, St. Jude Children’s Research Hospital, Memphis, TN, USA

    Shengdar Q. Tsai

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  1. Shengdar Q. Tsai
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Correspondence to Shengdar Q. Tsai.

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Tsai, S.Q. Towards safe therapy for immunodeficiency. Nat Biomed Eng 1, 937–938 (2017). https://doi.org/10.1038/s41551-017-0174-x

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