Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.


Potent drugless dendrimers

A dendrimer that depletes bioavailable copper as a result of its internal make-up displays powerful anticancer activity in mice, and no observable adverse effects.

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Fig. 1
Fig. 2


  1. Tomalia, D. A., Christensen, J. B. & Boas, U. (eds) Dendrimers, Dendrons and Dendritic Polymers (Cambridge Univ. Press, Cambridge, UK, 2012).

  2. Mintzer, M. A. & Grinstaff, M. W. Chem. Soc. Rev.40, 173–190 (2011).

    CAS  Article  Google Scholar 

  3. Shao, S. et al. Nat. Biomed. Eng. (2017).

    CAS  Article  Google Scholar 

  4. Svenson, S. Chem. Soc. Rev.44, 4131–4144 (2015).

    CAS  Article  Google Scholar 

  5. Walter, M. V. & Malkoch, M. Chem. Soc. Rev.41, 4593–4609 (2012).

    CAS  Article  Google Scholar 

  6. Gupte, A. & Mumper, R. J. Cancer Treat. Rev.35, 32–46 (2009).

    CAS  Article  Google Scholar 

  7. Brady, D. C. et al. Nature509, 492–496 (2014).

    CAS  Article  Google Scholar 

  8. Starpharma Successful VivaGel® Phase 3 Results and NDA Planned for rBV (7 August 2017).

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Ling Peng.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Lyu, Z., Peng, L. Potent drugless dendrimers. Nat Biomed Eng 1, 686–688 (2017).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer