Drug delivery

Ultrasound-triggered pain relief

The ability to release an anaesthetic from liposomes by applying ultrasound opens up the possibility of managing localized pain on-demand.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Fig. 1: Application of ultrasound to anaesthetic-loaded liposomes.


  1. 1.

    Weiser, T. G. et al. Lancet 372, 139–144 (2008).

    Article  PubMed  Google Scholar 

  2. 2.

    Leone, S. et al. Acta Biomed. 79, 92–105 (2008).

    CAS  PubMed  Google Scholar 

  3. 3.

    Kuusniemi, K. & Poyhia, R. J. Pain Res. 9, 25–36 (2014).

    Google Scholar 

  4. 4.

    Rwei, A. Y. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-017-0117-6 (2017).

Download references

Author information



Corresponding author

Correspondence to Patrick Couvreur.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Couvreur, P. Ultrasound-triggered pain relief. Nat Biomed Eng 1, 625–626 (2017). https://doi.org/10.1038/s41551-017-0121-x

Download citation


Sign up for the Nature Briefing newsletter for a daily update on COVID-19 science.
Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing