Biosensing: CRISPR-powered diagnostics

A CRISPR-associated nuclease that can promiscuously cleave RNAs enables a rapid and cheap test for the single-molecule detection and single-base discrimination of nucleic acids.

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Figure 1: CRISPR-based nucleic acid detection4.

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Correspondence to Chunhai Fan or Hong-Yuan Chen.

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Zuo, X., Fan, C. & Chen, H. Biosensing: CRISPR-powered diagnostics. Nat Biomed Eng 1, 0091 (2017). https://doi.org/10.1038/s41551-017-0091

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