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Drug delivery: Week-long diabetes therapy

A subcutaneous depot of a diabetes drug fused to a thermosensitive biopolymer leads to blood-glucose control, for over one week after a single injection, in animal models of type-2 diabetes.

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Figure 1: Long-acting release of an analogue of the glucagon-like peptide-1 receptor agonist via fusion with a thermosensitive elastin-like polypeptide.

References

  1. Ismail-Beigi, F. N. Engl. J. Med. 366, 1319–1327 (2012).

    Article  CAS  Google Scholar 

  2. Meloni, A. R., DeYoung, M. B., Lowe, C. & Parkes, D. G. Diabetes Obes. Metab. 15, 15–27 (2013).

    Article  CAS  Google Scholar 

  3. Gupta, V. Indian J. Endocrinol. Metab. 17, 413–421 (2013).

    CAS  Google Scholar 

  4. Luginbuhl, K. M. Nat. Biomed. Eng. 1, 0078 (2017).

    Article  Google Scholar 

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Correspondence to Omid Veiseh.

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Veiseh, O. Drug delivery: Week-long diabetes therapy. Nat Biomed Eng 1, 0090 (2017). https://doi.org/10.1038/s41551-017-0090

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