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Joint implants: An elution solution

An optimized drug-eluting polymer for the surface of articulating artificial joints may make them infection-free.

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Figure 1: A ball-and-socket hip-joint replacement.
Figure 2: An antimicrobial-eluting implant can prevent periprosthetic infection.


  1. Glyn-Jones, S. et al. The Lancet 386, 376–387 (2015).

    Article  CAS  Google Scholar 

  2. Otto M. Annu. Rev. Med. 64, 175–188 (2013).

    Article  CAS  Google Scholar 

  3. Sharkey, P. F., Lichstein, P. M., Shen, C., Tokarski, A. T. & Parvizi, J . J. Arthroplasty 29, 1774–1778 (2014).

    Article  Google Scholar 

  4. Kurtz, S. M., Lau, E., Watson, H., Schmier, J. K. & Parvizi, J. J. Arthroplasty 27, 61–65.e1 (2012).

    Article  Google Scholar 

  5. Chen, A. F., Heller, S. & Parvizi, J. Surg. Clin. North Am. 94, 1265–1281 (2014).

    Article  Google Scholar 

  6. Hickok, N. J. & Shapiro, I. M. Adv. Drug Delivery Rev. 64, 1165–1176 (2012).

    Article  CAS  Google Scholar 

  7. Suhardi, V. J. et al. Nat. Biomed. Eng. 1, 0080 (2017).

    Article  Google Scholar 

  8. Fink, B., Vogt, S., Reinsch, M. & Büchner, H. Clin. Orthop. Relat. Res. 469, 3141–3147 (2011).

    Article  Google Scholar 

  9. Collier, J. P. et al. Clin. Orthop. Relat. Res. 414, 289–304 (2003).

    Article  Google Scholar 

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Correspondence to Noreen J. Hickok.

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Hickok, N. Joint implants: An elution solution. Nat Biomed Eng 1, 0087 (2017).

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