Table 2 Percentage of cells transfected with mRNAs expressing membrane-associated forms of RSV F protein that are bound by D25, 4D7, or AM14.

From: Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infection

mRNA (µg) D25+ (%) 4D7+ (%) AM14+ (%)
mF    
0.17 2.2 1.3 3.0
0.3 6.0 2.1 7.9
0.8 20.4 13.7 9.4
1.7 27.4 39.7 20.8
2.5 26.1 40.4 22.0
mDS-Cav1    
0.17 0.4 0.6 0.4
0.3 2.7 1.7 1.9
0.8 15.4 3.9 8.8
1.7 36.7 14.9 21.6
2.5 44.9 12.4 27.4
RSV F7    
0.17 4.9 18.5 0.0
0.3 10.3 32.9 0.0
0.8 45.7 80.6 0.7
1.7 63.2 88.9 0.8
2.5 62.7 91.7 0.5
no mRNA    
0.0 0.0 0.0
0.0 0.0 0.0
0.0 0.0 0.2
0.1 0.3 1.4
0.6 0.8 0.5