Table 1 Current malaria vaccines under preclinical development or in clinical trials
From: Advances in malaria vaccine development: report from the 2017 malaria vaccine symposium
| Parasite stage | Vaccine classification | Current status |
|---|---|---|
| Pre-erythrocytic stage | ||
| PfSPZ vaccine | Whole organism (radiation attenuation) | Phase II |
| GAP vaccines | Whole organism (genetic attenuation) | Phase I |
| RTS,S | Subunit | Phase IV |
| CVac | Whole organism (chemical attenuation) | Phase I |
| Blood stage | ||
| Chemically attenuated parasites | Whole organism | Preclinical |
| AMA1-RON2 | Subunit | Preclinical |
| PfRH5 | Subunit | Phase I |
| Mosquito stage (TBVs) | ||
| Pfs25 | Subunit | Phase I |
| Pfs230 | Subunit | Phase I |
| Pfs47 | Subunit | Preclinical |
