Fig. 3 | npj Science of Food

Fig. 3

From: A low-carbohydrate ketogenic diet induces the expression of very-low-density lipoprotein receptor in liver and affects its associated metabolic abnormalities

Fig. 3

Schematic illustrations of VLDL dynamics and metabolism in LCKD-fed mice. Overview of VLDL dynamics and metabolism in chow-fed wild-type a, LCKD-fed wild-type mice b, chow-fed ob/ob mice c, and LCKD-fed ob/ob mice d. The size and number of objects are drawn to reflect the experimental results. The working hypothesis regarding the effect of hepatic VLDLR on VLDL is as follows: (i) in wild-type mice, LCKD induces hepatic VLDLR expression, which inhibits triglyceride (TG) secretion via VLDL; (ii) in ob/ob mice, LCKD induces hepatic VLDLR expression, whereas the VLDLR does not function for TG-rich VLDL, which is specifically generated in the ob/ob strain. Ch, cholesterol; FA, fatty acid

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