Table 1 RHCIII-MPC implants and summary of pre-operative patient diagnoses: (A) Characteristics of corneal implants used in the study (n = 3); (B) Summary of pre-operative patient diagnoses

From: Biomaterials-enabled cornea regeneration in patients at high risk for rejection of donor tissue transplantation

A     
Properties Transmission in white light (%) Refractive index Denaturation temperature (°C) Water content (%)
Implants 92.4 ± 0.122 1.334 ± 0.000322 51.0 ± 1.51 89.37 ± 2.1
QC acceptance criteria ≥85 1.1–1.5 ≥50 ≥85
Human cornea 87.1 ± 2.023 1.373–1.38024 65.126 7825
B        
Cause Age Gender Stage of disease Diagnosis LESCD Vascularised? Start of disease until treatment (m)
Infection
 Patient 1 64 F Acute Herpes simplex keratitis No No 5
 Patient 2 36 F Scar Fungal keratitis No No 8
 Patient 3 56 M Scar Herpes simplex keratitis No No 72
Burns
 Patient 4 58 F Acute Alkali burn Yes Yes 480
 Patient 5 73 M Acute Thermal burn (senile cataract in lens that impeded vision) Yes Yes 7
Other
 Patient 6 76 M Acute Rejected graft (no light perception due to glaucoma) Yes Yes 3
 Patient 7 47 M Acute Neurotrophic keratitis Yes No 13
  1. Other underlying, pre-existing conditions are shown in brackets