Fig. 2 | npj Regenerative Medicine

Fig. 2

From: Injection of embryonic stem cell derived macrophages ameliorates fibrosis in a murine model of liver injury

Fig. 2

M1 and M2 stimulation of ESDMs and BMDMs. Griess nitric oxide assay of naïve, M1 and M2-stimulated BMDMs and ESDMs (a), and expression of key markers by qRT-PCR analyses, iNos (b) and Cd86 (c) as markers of M1, Arg1 (d) and Fizz1 (e) as markers of M2 phenotypes, and Tweak (f), Mmp9 (g), Mmp12 (h), and Mmp13 (i) as markers of tissue remodeling. Quantification of phagocytosis of M1-and M2-stimulated BMDMs (j) and ESDMs (k). [*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; n = 3 per group, Two-way ANOVA with Tukey’s multiple comparison test]

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